Tennessee Titans at Indianapolis Colts Betting Preview

Sunday, November 29, 2020, Lucas Oil Stadium, Indianapolis. 1 p.m. ET

Titans at Colts Betting Preview: Titans (+3/-105), Colts (-3/-102)

Tennessee Titans

The Titans (7-3) might have 10 players on injured reserve for this game, so their depth will be tested. The holes that need to be plugged are on offense, defense and special teams.

The defense had trouble at times in the first matchup with the Colts, and now leading tackler Jayon Brown (76 stops) has landed on the injured list with a severe elbow injury. It has been a grueling stretch for the Titans, who needed overtime to win last week at Baltimore.

The good thing for Tennessee might be that they have physical running back Derrick Henry, who can dish out some punishment and is the league’s leading rusher this season with 1,079 yards. But the Titans managed only 294 yards of totals offense against the Colts when they lost 34-17 in the team’s meeting earlier this month.

Indianapolis Colts

The Colts (7-3) could take a huge step in the AFC South race if they complete a regular-season sweep of the Titans. Indianapolis won the first meeting just 17 days prior to this second scheduled encounter. The Colts will aim for their second three-game winning streak of the season.

Quarterback Philip Rivers threw for 308 yards in the first matchup with Tennessee. He had running back Nyheim Hines making big plays in that game, as the latter scored two touchdowns. The Colts are 4-1 under coach Frank Reich in his matchups with Titans coach Mike Vrabel.

Titans at Colts Betting Pick for Week 12

The Titans should come in with some confidence after knocking off Baltimore. This is a team that has relied on defense and yet it still needs to get some of that swagger back.

The Colts should be feeling good, too, after following their victory against Tennessee with last week’s comeback triumph against Green Bay. This will be a test if Rivers can put together another solid performance.

Titans at Colts Betting Pick:Colts 30, Titans 27

Titans at Colts Best Bet for Week 12

The Colts have scored at least 31 points in four of their past five games. Much of the tone of this game probably will depend on how the Indianapolis defense fares because the Titans are bound to come in with a better game plan this time.

The Colts looked vulnerable in the first half last week against Green Bay, then locked down for a sterling second half of defense. In eight of the last 11 Titans-Colts games, at least one of the teams has scored 30 points. For the season, Titans’ games have averaged 53.8 points per game.

Titans at Colts Best Bet: OVER 51.5 total points (-110)